I never use Drano. Most drain clogs are either hair (shower/tub) or cooking grease, either of which is easier & more effective to clear with a snake. I do have a plumber's snake, but I usually use a plastic zip-snake, they sell them at Menards right by the registers. They are about $2. They look like a super-size zip-tie, about 2 feet long with little teeth on the plastic. Poke it in the drain, then pull out all the gunk.
Drano will not dissolve a substantial hair clog. What it will do is melt the hair together and attract soap residue to the hairball, making it even worse. It will eventually have to be manually removed.